Brain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction - 02/07/25

Doi : 10.1016/j.tjpad.2025.100134

Sylvie Belleville ^a,^b,^⁎ , Nicole D. Anderson ^c,^d, Louis Bherer ^a,^e,^f, Richard Camicioli ^g,^h, Julie Carrier ^b,ⁱ, Senny Chan ^d, Marc Cuesta ^a, Thien Thanh Dang-Vu ^a,^j, Emily Dwosh ^k,^l, Alexandra J. Fiocco ^m, Guylaine Ferland ^f,ⁿ, Brigitte Gilbert ^o, Elaine Harris ^p, Inbal Itzhak ^q, Pamela Jarrett ^r,^s, Mohamed Abdelhafid Kadri ^a, Danielle Laurin ^t, Teresa Liu-Ambrose ^u,^v,^w, Chris A. McGibbon ^x, Laura Middleton ^y, Lesley Miller ^p, Haakon B. Nygaard ^k,^l, Manuel Montero-Odasso ^z,^aa,^bb, Kelly Murphy ^d, Natalie Phillips ^cc, M. Kathleen Pichora-Fuller ^d, Julie M. Robillard ^k, Eric E. Smith ^dd,^ee, Mark Speechley ^kk, Amal Trigui ^a,ⁿ, Walter Wittich ^ff, Howard Chertkow ^c,^q,^gg,^hh, Howard H. Feldman ^ii,^jj
the CTU expert group for the Canadian Consortium on Neurodegeneration in Aging (CCNA), CAN-THUMBS UP Study Group
^a Centre de recherche de l'Institut universitaire de gériatrie de Montréal, Montréal, Québec, Canada
^b Département de psychologie, Université de Montréal, Montréal, Québec, Canada
^c Rotman Research Institute, Baycrest Academy for Research & Education, Toronto, Ontario, Canada
^d Departments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada
^e Département de médecine, Université de Montréal, Montréal, Québec, Canada
^f Montreal Heart Institute, Montréal, Québec, Canada
^g Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
^h Neuroscience and Mental Health Institute, Edmonton, Alberta, Canada
ⁱ Center for Advanced Research in Sleep Medicine (CARSM), Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada
^j Department of Health, Kinesiology and Applied Physiology, Concordia University, Montréal, Québec, Canada
^k Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
^l Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
^m Institute for Stress and Wellbeing Research, Department of Psychology, Toronto, Canada
ⁿ Département de nutrition, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada
^o Clinique Bien Vieillir, Montréal, Québec, Canada
^p Co-president of Citizen Advisory Group, Canada
^q Lady Davis Institute for Medical Research, Montréal, Québec, Canada
^r Faculty of Medicine, Department of Internal Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
^s Department of Geriatric Medicine, Horizon Health Network, Saint John, New Brunswick, Canada
^t Centre d'excellence sur le vieillissement de Québec, CIUSSS de la Capitale-Nationale, INAF, Université Laval, Québec, Canada
^u Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada
^v Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, Canada
^w Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada
^x Faculty of Kinesiology and Institute of Biomedical Engineering, University of New Brunswick, Fredericton NB, Canada
^y Department of Kinesiology and Health Sciences, University of Waterloo, Ontario, Canada
^z Lawson Health Research Institute, London, Ontario, Canada
^aa Gait and Brain Lab, Parkwood Institute, University of Western Ontario, London, Ontario, Canada
^bb Departments of Medicine and Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada
^cc Department of Psychology, Concordia University, Montréal, Québec, Canada
^dd Hotchkiss Brain Institute, Calgary, Alberta, Canada
^ee Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
^ff École d'optométrie, Université de Montréal, Montréal, Québec, Canada
^gg Department of Medicine (Neurology), University of Toronto, Toronto, Ontario, Canada
^hh Department of Neurology and Neurosurgery, McGill University, Canada
ⁱⁱ Department of Neurosciences, University of California, San Diego, California, USA
^jj Alzheimer's Disease Cooperative Study, School of Medicine, University of California. San Diego California USA
^kk Department of Epidemiology & Biostatistics, Schulich Interfaculty Program in Public Health, Western University

^⁎Corresponding author at: Centre de recherche de l'Institut Universitaire de gériatrie de Montréal, CIUSSS du Centre-Sud-de-l’Île-de-Montréal, University of Montreal, 4565, Chemin Queen-Mary, Montréal Québec H3W 1W5, Canada.Centre de recherche de l'Institut Universitaire de gériatrie de MontréalCIUSSS du Centre-Sud-de-l’Île-de-MontréalUniversity of Montreal4565, Chemin Queen-MaryQuébecMontréalH3W 1W5Canada

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Abstract

Background

Online educational programs focused on ways to improve brain health could increase participant literacy, empowerment, and engagement in activities that support personal brain health, potentially reducing dementia risk.

Objectives

Our goal was to develop an evidence-based online educational program with a focus on risk and protective factors for dementia. Here we present the rationale and features of the program and include results from a pilot study that assessed usability and acceptability.

Design

This project is part of the Can-Thumbs UP (CTU) initiative. An Intervention Mapping Approach framework and co-construction approach was used to develop the online program. A pre-post pilot open label design was used to test the usability and acceptance of this at-home educational program.

Setting

The program and assessment for the pilot study were delivered fully remotely.

Participants

Twenty community-dwelling older adults (60–83 years of age, 65 % female) living in Canada who were at increased risk of dementia.

Program

The Brain Health PRO/Santé Cerveau PRO is a web-based 45-week program available in French and English. It provides general information and guidance on seven modifiable risk factors for dementia: physical activity, nutrition, cognitively stimulating activities, sleep, social and psychological health, vascular health, and vision/hearing. After completing a brief intake questionnaire, users are provided with an individualized risk profile to personalize priorities and goals. During the course of the program, users receive feedback on lifestyle changes. For this pilot study, participants completed a 15-week version of the program.

Measurements

This pilot study reports measures of usability (System Usability Scale), acceptance (Technology Acceptance Model-2) as well as risk profiles at intake based on self-reported questionnaires.

Results

Two logic models were developed to identify the determinants of risk for dementia and how these could be targeted by the program. A review of dementia risk and protective factors and online educational programs for older adults, as well as co-creation activities with experts, stakeholders, and citizen advisors, were used to identify the determinants, target, format, and content of the program. The pilot study reports excellent usability and acceptance with scores of 80.4/100 and 93.5/120 respectively.

Conclusion

Intervention mapping and co-construction approaches facilitated the design of a program that effectively balances the delivery of scientific content with the specific constraints, needs and abilities of older adults.

Trial registration

NCT05347966.

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Keywords : Alzheimer's disease, prevention, multidomain interventions, computer assisted training, modifiable risk factors

Plan

Introduction

Methods

Design process

Brain health PRO/Santé cerveau PRO pilot study

Results

Design process of the brain health PRO/Santé cerveau PRO

Results of Brain Health PRO/Santé Cerveau PRO pilot study

Discussion

Disclosure statement

CRediT authorship contribution statement

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Vol 12 - N° 6

Article 100134- juin 2025 Retour au numéro

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Brain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction - 02/07/25

Abstract

Background

Objectives

Design

Setting

Participants

Program

Measurements

Results

Conclusion

Trial registration

Plan

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