The aim of this paper is to discuss the question of complexity of sexuality in relation to the transformation of epistemological, methodological and interpretative paradigms of sexuality in post-modern age, linked to the affirmation of new constructs about gender, gender identity and sexual orientation.

Starting with a psychosocial approach and a dynamic-clinic orientation, the reflection is centred on the analysis of the implications for clinic of the conceptual modification of theory about sexuality (considered as a social construct).

Nowadays itʼs possible to find the affirmation of new genders and subjectivities which underline the importance of a “situated knowledge”, against dualistic logics of reality interpretation: queer, eccentric, nomadic, radical subjectivities, cyborgs, transgenders. Itʼs possible to categorise seventeen configurations of sexual orientation. Following this conceptual system, how the clinic can analyse the question of identification/recognition/admission of these alternative sexual realities? Which categories itʼs important to acquire to support (when itʼs necessary) individuals who deconstruct the old way to manage condition/situation care about sexuality?

Itʼs necessary in sexual clinical field a strong revision of the categories to set the reflection about sexuality, taking on interpretative models of sexual differences which consider the new subjectivities’ condition/needs that cannot be disregarded, because post-modern “subjectivity” needs to find the right criteria to represent itself, adequate symbolic spaces to express its complexity/multidimensionality, and specific categories to be read in a clinical-dynamic point of view.