Performance of magnetic resonance imaging in discriminating between intra- and extradural versus extradural-only nerve sheath tumor - 01/11/25
Highlights |
• | MRI features can help identify tumors with both intra- and extradural extension. |
• | CSF claw sign on MRI is a strong indicator of intradural tumor involvement. |
• | Candy shape appearance suggests a tumor passing anatomical barriers like the dura. |
• | These MRI signs showed excellent agreement between different radiologists. |
• | Identifying intradural extension preoperatively aids surgical planning and safety. |
Abstract |
Study design |
Retrospective cohort study.
Summary of background data |
Preoperative identification of intradural extension in nerve sheath tumors (NSTs) is crucial for surgical planning. While MRI is the primary imaging modality, reliable markers distinguishing intra- and extradural (IED) from extradural-only (EDO) NSTs remain uncertain.
Objective |
To assess the diagnostic utility of MRI features in differentiating IED from EDO NSTs.
Methods |
Forty-five patients with confirmed IED or EDO NSTs were retrospectively reviewed. Two radiologists analyzed MRI features, including cerebrospinal fluid (CSF) claw sign and candy shape, with interobserver agreement assessed. Fisher’s exact test and receiver operating characteristic analysis were performed.
Results |
Nine cases were IED, and 36 were EDO NSTs. Interobserver agreements of all imaging features between the two radiologists were excellent. IED tumors showed significantly more CSF claw sign and candy shape, and the prediction performance was assessed for these two imaging features. The CSF claw sign showed AUC values of 0.875 and 0.889, while the candy shape showed AUC values of 0.847 and 0.958.
Conclusion |
CSF claw sign and candy shape are useful MRI findings to differentiate between IED and EDO NSTs.
Le texte complet de cet article est disponible en PDF.Keywords : Nerve sheath neoplasms, Magnetic resonance imaging, Dura mater, Spinal cord neoplasms, Sensitivity and specificity
Abbreviations : NST, IED, EDO, MR
Plan
Vol 72 - N° 1
Article 101737- janvier 2026 Retour au numéro
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