Multimodality imaging plays a critical role in the evaluation of prosthetic valve function. Although echocardiography—both transthoracic and transesophageal—remains the first-line diagnostic tool, complementary imaging modalities such as cardiac computed tomography, cardiac MRI, and PET provide valuable additional information. Accurate assessment of prosthetic valve dysfunction often requires an integrative imaging approach owing to the complexity of structural and functional abnormalities. This article outlines the strengths and limitations of each imaging modality and presents illustrative clinical cases that demonstrate the necessity of a multimodal strategy in diagnosing and managing prosthetic valve complications.