S22-03 Updateon recent research with the hypomania checklist HCL-32 - 17/03/09
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Résumé |
Background |
The Hypomania Checklist HCL-32 (Angst et al. 2005) is still in development as a screening instrument for hypomania in depressed patients and as a research tool.
Update |
The original HCL-32 was slightly modified, omitting one tricky question on consequences (HCL-32 R1) and recently (HCL-32 R2) by adding two new symptoms (gambling and overeating). It is currently available in 27 languages.
New investigations include a Europe-wide GAMIAN study, individual studies in Brazil, Tunisia, Lebanon, Turkey, Korea, Taiwan and China, and the ongoing worldwide multicentre BRIDGE study.
Results |
1. | new data have been collected on the re-test reliability in China and Sweden and correlations with the Mood Disorder Questionnaire in Brazil; |
2. | exploratory and confirmatory factor analysis re-confirmed a two-factor structure (elated/overactive vs. irritable/risk taking) of the self-assessed hypomanic syndrome, replicable in over 1500 subjects from the community and patients with mood disorders across all cultures so far analysed; |
3. | total item scores have repeatedly been shown to be independent of the current mood state (normal, low, high); |
4. | adolescents/young adults in love feel high, and score comparably to bipolar-II patients on the HCL-32 (Brand et al 2007); |
5. | 89% of bariatric patients were also found to be high scorers on the HCL-32 (Alciati et al. 2007); |
6. | studies with the HCL-32 in subjects with alcohol use disorders (AUD) (previously shown to be strongly associated with bipolarity) are ongoing. |
Future goals |
Trans-cultural comparisons and evaluation of the questions on the consequences of hypomania for case-definition.
Le texte complet de cet article est disponible en PDF.Vol 24 - N° S1
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