Subcutaneous panniculitis-like T-cell lymphoma is an uncommon form of cutaneous lymphoma in the pediatric population. It is characterized histologically by subcutaneous infiltration of pleomorphic cytotoxic T cells, mimicking a lobular panniculitis. Although usually described as having an indolent clinical course, the condition may be complicated by systemic involvement and hemophagocytic syndrome, resulting in a poorer prognosis. We present two pediatric patients with aggressive forms of subcutaneous panniculitis-like T-cell lymphoma complicated by hemophagocytic syndrome, and discuss the current literature.Le texte complet de cet article est disponible en PDF.
Key words : ⍺/β, T cells, chemotherapy, cytophagic histiocytic panniculitis, hemophagocytic syndrome, subcutaneous panniculitis-like T-cell lymphoma
Abbreviations used : CHOP, CHP, SPTCL
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