Psoriatic arthritis is a strong predictor of sleep interference in patients with psoriasis - 08/08/11
, Bob Wong, PhD b, Elizabeth J. Horn, PhD c, d, Gerald G. Krueger, MD a
Correspondence to: Kristina Callis Duffin, MD, Department of Dermatology, University of Utah, 4A330 School of Medicine, 30 N 1900 East, Salt Lake City, UT 84132.Abstract |
Objective |
We sought to determine what clinical features of psoriasis predict sleep interference.
Methods |
Data were obtained from 420 respondents to the 2005 National Psoriasis Foundation telephone and e-mail surveys. Logistic regression was used to determine whether disease severity, body mass index, age of onset, psoriatic arthritis, income, ethnicity, sex, current therapy, and quality-of-life measures predicted reported sleep interference within the last month.
Results |
Psoriatic arthritis was the most significant predictor of sleep disturbance (odds ratio = 3.26). Itch, pain of lesions, and impact on emotional well-being were also significant predictors (odds ratio 1.26, 1.22, and 1.18, respectively). Body surface area covered with psoriasis, body mass index, and therapy were not significant predictors of sleep interference.
Limitations |
All data were self-reported and not physician-assessed.
Conclusions |
History of psoriatic arthritis, presence of itch and pain of psoriatic lesions, and impact of psoriasis on overall emotional well-being predict sleep interference.
Le texte complet de cet article est disponible en PDF.Key words : National Psoriasis Foundation, psoriasis, psoriatic arthritis, sleep
Plan
| Funding sources: None. |
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| Disclosure: Dr Horn was an employee of the National Psoriasis Foundation while a portion of this work was done. The National Psoriasis Foundation receives unrestricted funding from Abbott Immunology, Amgen Inc, Wyeth, Astellas Pharma Inc, BarrierTherapeutics, Beiersdorf, Centocor, Daavlin, Galderma Laboratories, Genentech, National Biologic Corp, Neutrogena, Photomedex, Stiefel Laboratories, and Warner Chilcott. Drs Callis Duffin, Wong, and Krueger have no conflicts of interest to declare. |
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| Presented in poster and abstract form at the International Investigative Dermatology Meeting, Kyoto, Japan, May 14-17, 2008. |
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| Reprints not available from the authors. |
Vol 60 - N° 4
P. 604-608 - avril 2009 Retour au numéro
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