The classic oral manifestations of vitamin B12 deficiency are considered nonspecific. We describe 4 patients with oral linear lesions associated with vitamin B12 deficiency. Patients were free of neurologic symptoms and anemia at diagnosis. We believe that glossitis with linear lesions is an early clinical sign of vitamin B12 deficiency. We recommend the determination of vitamin B12 in such patients, even in the absence of anemia.Le texte complet de cet article est disponible en PDF.
| Funding sources: None.
| Conflicts of interest: None declared.
| This work was presented as a poster at the XXXVI Spanish National Congress of Dermatology and Venereology, Barcelona, June 11-14, 2008; it received second place award to the best poster of the Congress.