Cutaneous symptoms of dermatomyositis significantly impact patients’ quality of life - 09/08/11

Doi : 10.1016/j.jaad.2004.12.015

Jennifer L. Hundley, MD ^a, Christie L. Carroll, MD ^a, Wei Lang, PhD ^b, Beverly Snively, PhD ^b, Gil Yosipovitch, MD ^a, Steven R. Feldman, MD, PhD ^a,^b, Joseph L. Jorizzo, MD ^a,^⁎
^a From the Center for Dermatology Research, Department of Dermatology
^b Department of Public Health Sciences, Wake Forest University School of Medicine

Reprint requests: Joseph L. Jorizzo, MD, Department of Dermatology, Medical Center Blvd, Winston-Salem, NC 27157-1071.

Winston-Salem, North Carolina

Abstract

Background

Dermatomyositis affects visible skin and causes disease symptoms that can affect patients’ quality of life (QOL).

Methods

In all, 71 patients with dermatomyositis or dermatomyositis sine myositis completed two QOL measures (the Skindex-16 and the Dermatology Life Quality Index) and a visual analog scale for pruritus. Disease severity was assessed by Physician’s Global Assessment.

Results

The mean Dermatology Life Quality Index score was 10.7 and the mean Skindex-16 score was 51.1. Itching contributed to impact on both the Dermatology Life Quality Index and Skindex-16. Females reported worse QOL.

Limitations

The effect of treatment on quality of life was not assessed in these analyses.

Conclusion

QOL impairment in dermatomyositis is greater than in other skin conditions including psoriasis and atopic dermatitis. Pruritus is an important treatable factor that significantly impacts QOL for patients with dermatomyositis.

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Abbreviations used : DLQI, PGA, QOL