Nail dystrophy and blisters as sole manifestations in myeloma-associated amyloidosis - 09/08/11
Doi : 10.1016/j.jaad.2005.12.031
Yasuyuki Fujita, MD a, ⁎ 
, Yukiko Tsuji-Abe, MD a, Kazuko C. Sato-Matsumura, MD, PhD b, Masashi Akiyama, MD, PhD a, Hiroshi Shimizu, MD, PhD a
, Yukiko Tsuji-Abe, MD a, Kazuko C. Sato-Matsumura, MD, PhD b, Masashi Akiyama, MD, PhD a, Hiroshi Shimizu, MD, PhD a a From the Departments of Dermatology, Hokkaido University Graduate School of Medicine
b Sapporo Social Insurance General Hospital
Reprint requests: Yasuyuki Fujita, MD, Department of Dermatology, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan.Sapporo, Japan
Abstract |
We report the case of a 61-year-old Japanese man with IgG λ-type multiple myeloma, who presented with nail dystrophy as the initial manifestation of systemic amyloidosis. Subsequently he developed bullous amyloidosis. This report documents these two rare signs of systemic amyloidosis and demonstrates the precise location of cutaneous blister formation and amyloid deposition by fluorescence antigen mapping and electron microscopy.
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| Funding sources: None. Conflicts of interest: None identified. |
© 2006
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 54 - N° 4
P. 712-714 - avril 2006 Retour au numéro
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