Early congenital syphilis and erythema multiforme–like bullous targetoid lesions in a 1-day-old newborn: Detection of Treponema pallidum genomic DNA from the targetoid plaque using nested polymerase chain reaction - 09/08/11
Taipei and Taoyuan, Taiwan
Abstract |
A 1-day-old male newborn was born with respiratory distress, low birth weight, hepatosplenomegaly, and bullous targetoid skin lesions over the face, back, buttocks, and extremities. A diagnosis of early congenital syphilis was made based on a treponemal serologic test. Pathologic examination of the skin lesion showed scattered dyskeratotic cells in the epidermis and interface dermatitis consistent with erythema multiforme. No spirochete could be found in the skin sections staining with Warthin-Starry stain. Using nested polymerase chain reaction, treponemal genomic DNA fragments encoding DNA polymerase I were detected.
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Production and distribution supported by an educational grant to the American Academy of Dermatology by Stiefel Laboratories, Inc. Funding sources: None. Conflicts of interest: None identified. |
Vol 55 - N° 2S
P. S11-S15 - août 2006 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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