A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: A randomized, physician-blinded, split-face comparative trial - 09/08/11
, Yuh-Mou Sue, MD c, Chih-Hsiung Yang, MD a, Chih-Kang Chen, MD a
Reprint requests: Chia-Chen Wang, MD, Department of Dermatology, Cardinal Tien Hospital, 362 Chung Cheng Rd, Hsin Tien City, Taipei County, 231, Taiwan.Taipei, Taiwan
Abstract |
Background |
Q-switched (QS) pigmented lasers and intense pulsed light (IPL) successfully treat pigment disorders.
Objective |
We sought to compare efficacy and side effects of QS alexandrite laser (QSAL) and IPL for freckle and lentigo treatment in Asians.
Methods |
In all, 15 patients with freckles and 17 patients with lentigines were treated randomly with one session QSAL in one cheek and two sessions IPL in the other cheek at 4-week intervals. Efficacy was determined using a new pigmentation area and severity index score.
Results |
All patients experienced improvement (P < .0001). Postinflammatory hyperpigmentation developed in one patient with freckles and 8 patients with lentigines after QSAL. No postinflammatory hyperpigmentation occurred after IPL. Freckles achieved greater improvement after QSAL than IPL (P = .04). In lentigines, the results after IPL were better than QSAL among those with postinflammatory hyperpigmentation after QSAL.
Limitations |
Limitations include a small case number and short follow-up period.
Conclusion |
QSAL was superior to IPL for freckle treatment. IPL should be used for lentigines in Asian persons.
Le texte complet de cet article est disponible en PDF.Abbreviations used : IPL, Nd:YAG, PIH, PSI, QS, QSRL, QSAL
Plan
| Funding sources: None. Conflicts of interest: None identified. |
Vol 54 - N° 5
P. 804-810 - mai 2006 Retour au numéro
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