Diagnosis of loxoscelism in a child confirmed with an enzyme-linked immunosorbent assay and noninvasive tissue sampling - 09/08/11
, Jonathan A. Green, PhD b, Hernan F. Gomez, MD c
Reprint requests: William V. Stoecker, MD, The Dermatology Center, 1702 E 10th St, Rolla MO 65401-4600.Rolla and Columbia, Missouri; and Ann Arbor, Michigan
Abstract |
Background |
Confirmation of mild bites caused by Loxosceles reclusa with swab testing has not been previously documented, to our knowledge.
Methods |
We report a case using an enzyme-linked immunosorbent assay (ELISA) test.
Results |
A lesion lacking necrosis or other specific signs of loxoscelism was confirmed by identification of the Loxosceles venom and further confirmed by identification of a spider found in the patient’s bed.
Limitations |
This is a pilot single-case report for this enzyme-linked immunosorbent assay test.
Conclusions |
A sensitive and specific enzyme-linked immunosorbent assay designed to detect Loxosceles venom, using a specimen obtained by swabbing the lesion, can aid in diagnosis of loxoscelism.
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| Supported by SpiderTech, Rolla, Missouri. Disclosure: Dr Stoecker owns a controlling interest in SpiderTech, which develops tests for spider bites and spider traps. Drs Stoecker, Green, and Gomez have filed a provisional patent for a diagnostic test for Loxosceles envenomations. |
Vol 55 - N° 5
P. 888-890 - novembre 2006 Retour au numéro
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