A case of Churg–Strauss syndrome associated with antiphospholipid antibodies - 12/08/11
Cleveland, Ohio
Abstract |
Churg–Strauss syndrome (CSS) is a systemic vasculitis affecting both small- and medium-sized blood vessels, almost invariably affecting the lung, and frequently associated with cutaneous involvement. Microvascular vaso-occlusion leading to digital gangrene is not a feature of CSS. We report an unusual case of a patient with CSS with antiphospholipid antibodies who developed severe digital gangrene in addition to cutaneous vasculitis. The presence of antiphospholipid antibodies is not a feature usually seen in association with CSS. While the full clinical spectrum of CSS is still being defined, the identification of additional features associated with this syndrome might help to better understand the pathogenesis of the disease and to have an impact on both management and prognosis.
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Supported by a National Institutes of Health National Institute of Arthritis and Musculoskeletal Skin Diseases grant to A. C. G. (no. RO1 AR049284-03) and the NIAMS Case Skin Disease Research Center (no. A1-39750). Conflicts of interest: None identified. Reprints not available from the authors. |
Vol 56 - N° 4
P. 701-704 - avril 2007 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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