The Preterm Prediction study: Association between maternal body mass index and spontaneous and indicated preterm birth - 18/08/11
, Robert L. Goldenberg, MD, Brian M. Mercer, MD, Jay D. Iams, MD, Paul J. Meis, MD, Atef H. Moawad, MD, Cora A. MacPherson, PhD, Steve N. Caritis, MD, Menachem Miodovnik, MD, Kate M. Menard, MD, Gary R. Thurnau, MD, Yoram Sorokin, MD
Reprint requests: Israel Hendler MD, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hutzel Hospital-Wayne State University, 3990 John R Rd, Detroit, MI 48201.Abstract |
Objective |
The purpose of this study was to evaluate the relationship between prepregnancy maternal body mass index and spontaneous preterm birth and indicated preterm birth.
Study design |
This was a secondary analysis of the Maternal-Fetal Medicine Units Network, Preterm Prediction study. Patients were classified into categories that were based on their body mass index. Rates of indicated and spontaneous preterm birth were compared.
Results |
Five hundred ninety-seven (20.5%) of 2910 women were obese. Obese women had fewer spontaneous preterm births at <37 weeks of gestation (6.2% vs 11.2%; P < .001) and at <34 weeks of gestation (1.5% vs 3.5%; P=.012). Women with a body mass index of <19 kg/m2 had 16.6% spontaneous preterm birth, with a body mass index of 19 to 24.9 kg/m2 had 11.3% spontaneous preterm birth, with a body mass index of 25 to 29.9 kg/m2 had 8.1% spontaneous preterm birth, with a body mass index of 30 to 34.9 kg/m2 had 7.1% spontaneous preterm birth, and with a body mass index of ≥35 kg/m2 had 5.2% spontaneous preterm birth (P < .0001). Indicated delivery was responsible for an increasing proportion of preterm births with increasing body mass index (P=.001). Obese women had lower rates of cervical length <25 mm (5% vs 8%; P=.012). Multivariable regression analysis confirmed a lower rate of spontaneous preterm birth in obese gravid women (odds ratio, 0.57; 95% CI, 0.39-0.83; P=.003).
Conclusion |
Obesity before pregnancy is associated with a lower rate of spontaneous preterm birth.
Le texte complet de cet article est disponible en PDF.Key words : Maternal obesity, Spontaneous preterm birth, Body mass index
Plan
| Supported by grants from the National Institute of Child Health and Human Development: HD27917, HD27869, D27915, HD27860, HD27861, HD21410, HD27889, HD21410, HD 27905, HD27889, HD21414, HD27889, HD19897 and HD36801. Presented at the Society for Gynecologic Investigation annual meeting, March 22-27, 2004, Houston, Tex. |
Vol 192 - N° 3
P. 882-886 - mars 2005 Retour au numéro
Article précédent
- Factors predicting severe perineal trauma during childbirth: Role of forceps delivery routinely combined with mediolateral episiotomy
- Gernot Hudelist, Janos Gelle'n, Christian Singer, Ernst Ruecklinger, Klaus Czerwenka, Othmar Kandolf, Joerg Keckstein
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- Rodney K. Edwards, Ronald J. Ferguson, Jonathan J. Shuster, Douglas Theriaque, Susan Gentry, Patrick Duff
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