Hemophagocytic syndrome presenting with a facial erythema in a patient with systemic lupus erythematosus - 19/08/11
, Sawa Otsubo, MD b, Takanori Miura, MD, PhD c, Hajime Iizuka, MD, PhD b
Reprint requests: Hiroyuki Sakai, MD, PhD, Department of Dermatology, Asahikawa City Hospital, 1-1-65 Kinsei-cho, Asahikawa, Hokkaido 070-8610, Japan.Abstract |
Hemophagocytic syndrome is a systemic reactive histiocytic proliferative disorder affecting the reticuloendothelial system. Skin lesions develop in 12.5% to 55.6% of the patients. We report a 35-year-old woman with systemic lupus erythematosus and Graves’ disease complicated with parvovirus B19–associated hemophagocytic syndrome. She presented with slightly infiltrated erythematous macules and plaques with ulcers on the scalp, face, and back. A skin biopsy specimen taken from an area of facial erythema demonstrated typical phagocytic cells in the skin. Hemophagocytic syndrome–associated specific cutaneous lesions should be included in the differential diagnosis of facial and nonfacial erythema in patients with systemic lupus erythematosus.
Le texte complet de cet article est disponible en PDF.Abbreviations used : HPS, IL, SLE
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| Funding sources: None. |
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| Conflicts of interest: None declared. |
Vol 57 - N° 5S
P. S111-S114 - novembre 2007 Retour au numéro
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