Multiple disseminated large-cell acanthomas of the skin associated with human papillomavirus type 6 - 21/08/11
Doi : 10.1016/j.jaad.2005.01.120
Thomas Berger, MD a, 
⁎ 
, Eggert Stockfleth, MD b, Thomas Meyer, PhD c, Franklin Kiesewetter, MD a, Jens Oliver Funk, MD a, †
⁎ , Eggert Stockfleth, MD b, Thomas Meyer, PhD c, Franklin Kiesewetter, MD a, Jens Oliver Funk, MD a, † a From the Departments of Dermatology, University of Erlangen-Nuremberg
b Berlin (Charité)
c Institute for Immunology, Pathology, and Molecular Biology, Hamburg
Correspondence to: Thomas Berger, MD, Department of Dermatology, Tawam Hospital, PO Box 15258, Al Ain, Abu Dhabi, United Arab Emirates.Erlangen, Berlin, and Hamburg, Germany
Abstract |
Cutaneous acanthomas encompass many clinically distinct types. We describe a patient with multiple nodules on the skin of the upper limbs which were histologically diagnosed as large-cell acanthomas. Further analysis revealed, surprisingly, the presence of human papillomavirus (HPV) type 6 within these lesions. HPV type 6 should therefore be considered an important cofactor in the pathogenesis of large-cell acanthomas.
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| Supported in part by a research grant from the Deutsche Forschungsgemeinschaft and the Michelangelo funds (to J. O. F). Conflicts of interest: None. |
© 2005
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 53 - N° 2
P. 335-337 - août 2005 Retour au numéro
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