Basal cell carcinomas with unusual histologic patterns - 21/08/11
Reprint requests: Pearon G. Lang, MD, Department of Dermatology, Medical University of South Carolina, 135 Rutledge Ave, 11th Floor, PO Box 250578, Charleston, SC 29425.Charleston, South Carolina
Abstract |
Uncommon histologic variants of basal cell carcinoma (BCC) can present a diagnostic challenge. In this case series, we describe 3 patients with unusual BCCs encountered in a dermatologic surgical unit over a 1-year period from September 2003 to September 2004. The formalin-fixed, paraffin-embedded histologic specimens were initially examined microscopically after staining with hematoxylin and eosin. Additional stains, including diastase periodic acid–Schiff, colloidal iron, carcinoembryonic antigen, and cytokeratin-20, were subsequently performed as appropriate. Of the 3 lesions, one exhibited apocrine differentiation and two demonstrated a trabecular growth pattern. Although BCCs demonstrating apocrine differentiation have previously been described, a trabecular growth pattern, to our knowledge, has not been previously reported for BCC.
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| Funding sources: None. Conflicts of interest: None. |
Vol 53 - N° 5
P. 833-837 - novembre 2005 Retour au numéro
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