High alcohol and low folate intake increases risk of major chronic disease in women - 24/08/11
Abstract |
Question |
Is there an association between alcohol and folate intake and the risk of cardiovascular disease and cancer in women?
Study design |
Cohort study with 16 year follow-up.
Main results |
At low to moderate levels of alcohol intake (0 to 30g/day) there was no association between folate intake and relative risk of major chronic disease (p-value for trend ⩾0.15). Heavy drinkers (>30g/day alcohol) with low folate intake (<180μg/day) had the highest risk of major chronic disease. Compared with teetotal women consuming folate 400–599μg/day, heavy drinkers with low folate intake had increased risks of major chronic disease (RR 1.36, 95% CI 1.10 to 1.70). Increased risks of cardiovascular disease associated with heavy drinking decreased among women with low folate intake, however to reduce risks associated with cancer, folate intake of ⩾600μg/day was required.
Authors’ conclusions |
Women who consume high levels of alcohol and low levels of folate are at significantly increased risk of major chronic disease.
Le texte complet de cet article est disponible en PDF.Keywords : Alcohol, Folic acid, Cancer, Cardiovascular diseases, Risks, Cohort study
Plan
 | Abstracted from: Jiang R, Hu FB, Giovannucci EL, et al. Joint association of alcohol and folate intake with risk of major chronic disease in women. Am J Epidemiol 2003; 158: 760–771. |
Vol 8 - N° 2
P. 71-73 - avril 2004 Retour au numéro
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