How safe and effective is Echinacea purpurea at reducing the duration and severity of upper respiratory tract infections in children?
Multicentre randomised controlled trial.
There was no significant difference in duration or severity of symptoms with Echinacea purpurea compared with placebo in children with upper respiratory tract infection (median duration of symptoms (95% CI): 9 days (8 to 10 days) with Echinacea vs. 9 days (8 to 10 days) with placebo; P=0.89; median severity of symptoms (95% CI): 33 (29 to 40) with Echinacea vs. 33 (30 to 38) with placebo; P=0.69). Rash occurred in significantly more children receiving Echinacea compared with placebo (reports of rash: 24 with Echinacea v 10 with placebo; P=0.008).
Echinacea purpurea is ineffective for treating upper respiratory tract infections in children aged 2 to 11 years.Le texte complet de cet article est disponible en PDF.
Keywords : Upper respiratory tract infections, Echinacea purpurea, Children, Randomised controlled trial
| Abstracted from: Taylor JA, Weber W, Standish L et al. Efficacy and safety of echinacea in treating upper respiratory tract infections in children. A randomized controlled trial. JAMA 2003; 290: 2824–2830.