What is the relationship between lung cancer mortality and tar rating of smoker's cigarette brand?
Multivariate analysis of data from prospective cohort study.
Risk of death due to lung cancer was significantly higher in smokers of high-tar cigarettes compared with people smoking low, very low and medium tar cigarettes (see Table 1). There were no significant differences in the risk of lung cancer mortality for people smoking very low or low tar cigarettes compared with smokers of medium tar cigarettes. Stopping smoking considerably reduced risk of lung cancer. People quitting before age 35 years had a very similar risk to those who had never smoked.
There was no detectable difference in risk of lung cancer among people who smoked very low, low or medium tar cigarettes. An increased risk was identified in people who smoked high tar cigarettes. These findings persisted after adjustment for demographics, diet and medical history and for cigarettes/day.Le texte complet de cet article est disponible en PDF.
Keywords : Smoking, Lung cancer, Risk factors, Yields, Cohort study
| Abstracted from: Harris JE, Thun MJ, Mondul AM et al. Cigarette tar yields in relation to mortality from lung cancer in the cancer prevention study II prospective cohort, 1982-8. BMJ 2004; 328: 72–76.