Acquired disorders of elastic tissue: part I. increased elastic tissue and solar elastotic syndromes - 24/08/11
Providence, Rhode Island
Abstract |
Elastic fibers in the extracellular matrix are an integral component of dermal connective tissue. The resilience and elasticity required for normal structure and function of the skin may be attributed to the network of elastic tissue. Advances in our understanding of elastic tissue physiology provide a foundation for studying the pathogenesis of elastic tissue disorders. Many acquired disorders are nevertheless poorly understood due to the paucity of reported cases. Several acquired disorders in which accumulation or elastotic degeneration of dermal elastic fibers produces prominent clinical and histopathologic features have recently been described. They include elastoderma, linear focal elastosis, and late-onset focal dermal elastosis and must be differentiated from better-known disorders, among them acquired pseudoxanthoma elasticum, elastosis perforans serpiginosa, and Favré-Racouchot syndrome.
Learning objective |
At the conclusion of this learning activity, participants should understand the similarities and differences between acquired disorders of elastic tissue that are characterized by an increase in elastic tissue, as well as the spectrum of solar elastotic dermatoses.
Le texte complet de cet article est disponible en PDF.Abbreviations : EPS, MMP, PXE
Plan
Funding sources: Supported in part by an unrestricted grant from PXE International, Inc. Conflicts of interest: None identified. Reprints not available from authors |
Vol 51 - N° 1
P. 1-21 - juillet 2004 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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