Treatment of recalcitrant scleromyxedema with thalidomide in 3 patients - 24/08/11
Winston-Salem, North Carolina, and Rome, Italy
Abstract |
Scleromyxedema is a generalized, papular, and sclerodermoid form of lichen myxedematosus associated with monoclonal gammopathy and systemic changes. Despite anecdotal reports of success with various agents, no satisfactory treatments are currently available. We report 3 adult patients with recalcitrant scleromyxedema associated with paraproteinemia who were treated with thalidomide. All 3 patients had marked improvement of the skin lesions and joint mobility after the first 2 months of therapy, with further amelioration after 4 months, and reduction in paraprotein levels.
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Funding sources: None. Conflicts of interest: None identified. |
Vol 51 - N° 1
P. 126-131 - juillet 2004 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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