The effect of two skin cleansing systems on moderate xerotic eczema - 24/08/11
Abstract |
Background |
Moderate xerotic eczema, characterized by stratum corneum desquamation, erythema, and pruritis is a common condition that can be induced or worsened by skin cleansing. Traditional dermatologic therapy includes the use of emollients, medium or high potency topical corticosteroids, and a change in bathing habits.
Objective |
To investigate the effect of two cleansing systems: a synthetic detergent bar soap applied with a cotton washcloth and a petrolatum-delivering body wash applied with a polyethylene puff as part of a topical treatment approach to moderate xerotic eczema.
Method |
Sixty patients with moderate xerotic eczema were enrolled in a 4-week investigator-blinded study. Half were randomly treated with a strong topical corticosteroid cream (0.05% fluocinonide) and a traditional cleansing system consisting of a synthetic detergent bar soap applied with a washcloth. The remaining patients were treated with a weaker, medium strength topical corticosteroid cream (0.1% triamcinolone acetonide) and a novel cleansing system consisting of a petrolatum-delivering body wash applied with a polyethylene puff. Dermatologist investigator evaluations and patient self-assessments were conducted at baseline, 2 weeks, and 4 weeks.
Results |
Patients using the novel petrolatum-delivering body wash and polyethylene puff cleansing system and the lower potency corticosteroid cream demonstrated significantly greater clinical improvement than those patients using the traditional cleansing system of a synthetic detergent beauty bar and washcloth system and the higher potency corticosteroid cream after both 2 and 4 weeks of treatment.
Conclusion |
The cleansing system of a petrolatum-delivering body wash delivered by a polyethylene puff may be useful as a cleanser for patients with moderate xerotic eczema.
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This work was funded by a grant from The Procter & Gamble Company. Disclosure: Dr Draelos has served as a paid consultant to The Procter & Gamble Company, but has no financial interest in the products studied as part of this research. Keith Ertel, PhD, Paula Hartwig, BS, and Gayle Rains, BA, are employees of The Procter & Gamble Company, Cincinnati, Ohio. Presented in part at the American Academy of Dermatology's 1999 Summer Meeting. |
Vol 50 - N° 6
P. 883-888 - juin 2004 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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