In vivo confocal microscopy can noninvasively image thin en face sections within living intact human tissue with high resolution and contrast. This evolving technique may provide clinicians with tools to help detect lentigo maligna lesion progression in vivo and may be important in defining tumor margins, thus providing a more definitive surgical eradication of lentigo maligna and malignant melanoma in situ, lentigo maligna type. We present a case of malignant melanoma in situ, lentigo maligna type, and we describe the images seen with confocal microscopy in correlation with routine histopathology. (J Am Acad Dermatol 2002;46:260-3.)Le texte complet de cet article est disponible en PDF.
| Supported in part by the US Department of Energy (grant DOE-FG0Z-91ER61228).
| Reprint requests: Salvador González, MD, PhD, Wellman Laboratories of Photomedicine, Barlett Hall 814, Department of Dermatology, Massachusetts General Hospital, 55 Blossom St, Boston, MA 02114.