Solitary fibrous tumor (SFT) is an uncommon tumor initially reported in the pleura but recently described in other sites of the body. We report a SFT of the skin that presented as painless nodule located in the right cheek in a 56-year-old woman. Histologically, the tumor was composed of spindle-shaped cells arranged in a patternless pattern of short and narrow fascicles with interspersed bundles of thick collagen, and numerous blood vessels with a focally hemangiopericytoma-like appearance. Immunohistochemically, the tumor cells strongly expressed vimentin, CD34 and bcl-2. The lesion was excised and the patient remains well at 16-month follow-up. This case presented some diagnostic difficulty because of its unusual location, and had to be distinguished from other superficial soft tissue tumors. Recognition of SFT in the skin is important to avoid possible confussion with a variety of spindle cell neoplasms with different biologic potential. (J Am Acad Dermatol 2002;46:S37-40.)Le texte complet de cet article est disponible en PDF.
|☆|| This supplement is made possible through an unrestricted educational grant from Stiefel Laboratories to the American Academy of Dermatology.
|☆☆|| Reprint requests: David Hardisson, MD, Servicio de Anatomía Patológica, Hospital General Universitario de Guadalajara, c/ Donantes de Sangre s/n, E-19002 Guadalajara, Spain. E-mail: firstname.lastname@example.org