Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine - 02/09/11
Abstract |
Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection. Severe rash, including the Stevens-Johnson syndrome (SJS), is the major toxicity of nevirapine and is described in the package labeling with a prominent, boxed warning. Though physicians treating large populations of patients with HIV are well aware of this complication, only one other report of nevirapine-associated SJS has been documented in the dermatology literature. We describe 2 cases of SJS related to nevirapine use and review the literature on this newly recognized association. (J Am Acad Dermatol 2001;44:354-7.)
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This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology. |
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Reprint requests: Adelaide A. Hebert, MD, Department of Dermatology, University of Texas Medical School at Houston, 6431 Fannin, MSB 1.186, Houston, TX 77030. E-mail: ahebert@utmmg.med.uth.tmc.edu |
Vol 44 - N° 2P2
P. 354-357 - février 2001 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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