Pemphigus foliaceus is an autoimmune blistering disease of unknown origin with antibodies produced against desmoglein 1, an adhesive protein found in the desmosomal cell junction in the suprabasal layers of the epidermis. The disease is primarily treated with corticosteroids and corticosteroid-sparing immunosuppressive agents. We report a case of pemphigus foliaceus successfully treated with mycophenolate mofetil. It remains to be seen whether this agent has a significant effect on the course of the disease and remission induction. (J Am Acad Dermatol 2000;42:514-5.)Le texte complet de cet article est disponible en PDF.
| Reprint requests: Kenneth H. Katz, MD, Penn State, Department of Medicine, Section of Dermatology, The Milton S. Hershey Medical Center, Hershey, PA 17033.