Treatment of severe atopic dermatitis by topical immune modulation using dinitrochlorobenzene - 05/09/11
Abstract |
We present the results of a small uncontrolled pilot trial which suggest that contact sensitization to dinitrochlorobenzene and repeated weekly applications significantly improve the clinical status of severe atopic dermatitis in adults. Although no changes were noted in circulating levels of either lymphocyte subset populations or the serum cytokines assayed in this trial, our observations may be due to topical immune modulation by dinitrochlorobenzene. Larger controlled studies of dinitrochlorobenzene treatment in atopic dermatitis are warranted. (J Am Acad Dermatol 2000;42:687-9.)
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 | Reprint requests: L. Bruce Mills, MD, Department of Dermatology and Research and Education Foundation, The Honolulu Medical Group, Inc, 550 S Beretania St, Honolulu, HI 96813. E-mail: lmills@pixi.com . |
Vol 42 - N° 4
P. 687-689 - avril 2000 Retour au numéro
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