Annular erythema of Sjögren's syndrome in a white woman - 05/09/11
Abstract |
Annular erythema of Sjögren's syndrome (AE-SS) is believed to be the Asian counterpart of subacute cutaneous lupus erythematosus (SCLE) in white persons. We report the second case of a white person with AE-SS, diagnosed by clinical and serologic findings, as well as the absence of histologic criteria for SCLE. The diagnosis of AE-SS was established by symptoms of xerophthalmia and xerostomia, as well as by examination of skin and salivary gland biopsy specimens. Evaluation showed the presence of anti-Ro(SS-A) and anti-La(SS-B) autoantibody, with the presence of anti-Ro(SS-A) antibody against the 60-kd, but not the 52-kd, epitope, a pattern frequently seen in both the Asians with AE-SS and in white patients with SCLE. Both skin and sicca symptoms were alleviated with combination antimalarial therapy, which included hydroxychloroquine and quinacrine. This case demonstrates that AE-SS can occur in white patients and that the autoantibody profile is similar to that described in Asians with this disease. (J Am Acad Dermatol 2000; 42:1069–73.)
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J Am Acad Dermatol 2000;42:1069–73 |
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Reprint requests: Victoria P. Werth, MD, Department of Dermatology, University of Pennsylvania, 36th and Spruce, Philadelphia, PA 19104. |
Vol 42 - N° 6
P. 1069-1073 - juin 2000 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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