Sarcoidosis in a patient with AIDS: A manifestation of immune restoration syndrome - 07/09/11
Abstract |
Sarcoidosis has been rarely reported in the presence of HIV infection. Helper T-lymphocyte depletion may attenuate granuloma formation. We present a patient who developed active sarcoidosis after being started on highly active antiretroviral therapy (HAART), which increased his CD4 count and decreased his viral load. There have been reports of exaggerated responses to mycobacteria and viruses with the restoration of T-cell function after HAART in HIV-infected patients. We propose that active sarcoidosis seen in this patient is also a manifestation of this newly observed “immune restoration disease.” (J Am Acad Dermatol 1999;41:285-6.)
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 | This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology. |
| This work was supported by a grant from the Center for AIDS Research P30AI27763. |
 | From the Departments of Dermatology,a Pathology,b and Medicine,c University of California, San Francisco. |
| Reprint requests: Paradi Mirmirani, MD, University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143-0316. E-mail: paradi@itsa.ucsf.edu |
| ♢ | 0190-9622/99/$8.00 + 0 16/4/98038 |
Vol 41 - N° 2S
P. 285-286 - août 1999 Retour au numéro
- Granuloma annulare localized to the palms
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