Necrobiotic cutaneous T-cell lymphoma - 07/09/11
Doi : 10.1016/S0190-9622(99)70332-4
A. Woollons, MRCPa, A. Darvay, MRCPb, S.M. Khorshid, MRCPc, S. Whittaker, MD, FRCPc, R.Russell Jones, FRCPa
London, United Kingdom
From the St John’s Institute of Dermatology,a St Thomas’s Hospital, London; Ealing Hospital NHS Trust,b Southall, Middlesex; and Department of Dermatology,c Royal Free Hospital, London, United Kingdom
Abstract |
We report 3 patients with granulomatous cutaneous T-cell lymphoma (CTCL) who showed necrobiosis histologically with palisading granulomas. Although granulomatous change may be present in up to 4% of cases of CTCL, necrobiosis is rare. Misdiagnosis may occur if epidermotropism is minimal or if atypical cells are masked by the granulomatous infiltrate. T-cell receptor gene analysis confirmed the presence of clonal T-cell populations in lesional skin from all 3 cases. (J Am Acad Dermatol 1999;41:815-9.)
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 | This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology. |
| Reprint requests: Dr A. Woollons, St John’s Institute of Dermatology, St Thomas’s Hospital, Lambeth Palace Road, London SE1 7EH, United Kingdom. |
 | 0190-9622/99/$8.00 + 0 16/4/99356 |
© 1999
American Academy of Dermatology, Inc. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 41 - N° 5S
P. 815-819 - novembre 1999 Retour au numéro
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