Results and side effects of dermatologic radiotherapy: A retrospective study of irradiated cutaneous epithelial neoplasms - 07/09/11
Background: |
Ionizing radiation therapy has a well-defined role among several therapeutic options available for the management of cutaneous neoplasms. However, many dermatologists today are not aware of its potential
Objective: |
Our purpose was to evaluate the effectiveness and safety of radiotherapy in a large series of patients with primary malignant epithelial neoplasms (PMENs), who had been subjected to radiotherapy between 1982 and 1995.
Methods: |
A retrospective study was performed on 1188 patients with a total of 2002 PMENs that had been treated by contact, superficial, and intermediate x-ray therapy.
Results: |
Complete remission was obtained in 98.7% of the irradiated lesions. The 5-year cure rate was 90.73%. Cosmetic results were evaluated as “good” or “acceptable” in 84.01% of the treated lesions. Acute complications occurred in 1.94% and chronic complications in 0.34%. To date, neither radio-induced skin neoplasms nor late stochastic effects have been observed.
Conclusion: |
This study confirms that dermatologic radiotherapy is an effective and reliable form of treatment of PMENs and has a favorable cure rate/toxicity ratio.
Le texte complet de cet article est disponible en PDF.
Vol 41 - N° 4
P. 589-594 - octobre 1999 Retour au numéro
Article précédent
- Effects of acitretin on the liver
- Henry H. Roenigk, Jeffrey P. Callen, Cynthia A. Guzzo, H. Irving Katz, Nicholas Lowe, Kathi Madison, Thomas Nigra, Virginia C. Fiedler, Robert B. Armstrong
- Contact immunotherapy with squaric acid dibutylester for the treatment of recalcitrant warts
- Alice N. Lee, Susan B. Mallory
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?