Helicobacter pylori infection in asymptomatic HBV carriers, alcohol users and normal adult population in Shandong Province, China - 07/09/11
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Summary |
Objective |
The purpose of this study was to investigate the prevalence of Helicobacter pylori (H. pylori) in asymptomatic HBV carriers (ASCs), alcohol users and in the normal adult population in the littoral region of Shandong, China.
Methods |
Two hundred and thirty-five ASCs, 573 alcohol users and 1637 nonalcoholic normal adults were recruited from January 2008 to June 2010. The H. pylori infection status of all participants was measured by serum immunoglobulin G antibodies using ELISA and 13C-urea breath test (UBT).
Results |
The prevalence of H. pylori infection in ASCs was 38.67%, which was not different than that in the normal adult population (35.94%, P=0.352). H. pylori infection (26.98%) was decreased in alcohol users with normal liver function tests compared to that in the normal adult population (P=0.014). Meanwhile, H. pylori infection was increased to 35.20% in alcohol users with abnormal liver function tests, which was significantly different compared with that of alcohol users with normal liver function tests (P=0.042).
Conclusion |
The epidemiological pattern of H. pylori infection in ASCs is the same as in the normal adult population, and moderate consumption may facilitate elimination of H. pylori infection in alcohol users while H. pylori infection is increased in alcohol users with abnormal liver function tests.
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Vol 35 - N° 8-9
P. 560-562 - septembre 2011 Retour au numéro
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