The pathogenesis of psoriasis and the mechanism of action of tazarotene - 09/09/11
Abstract |
The 3 major features of psoriasis—abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin—can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of these markers. Tazarotene helps to normalize the levels of the markers, thereby bringing about clinical improvement. (J Am Acad Dermatol 1998;39:S129-33.)
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Supported by Allergan Skin Care. |
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Reprint requests: Madeleine Duvic, MD, Box 47, Section of Dermatology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030. |
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0190-9622/98/$5.00 + 0 16/0/92887 |
Vol 39 - N° 4S
P. S129-S133 - octobre 1998 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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