Persistent supravenous erythematous eruption: A rare local complication of intravenous 5-fluorouracil therapy - 09/09/11
Abstract |
We describe a 47-year-old man who developed a linear serpentine erythematous eruption, overlying the superficial veins on both arms, after treatment with intravenous 5-fluorouracil. No evidence of superficial phlebitis or extravasation were observed. Histologically, a prominent vacuolar alteration of basal cells, necrotic keratinocytes, pigment incontinence, and a perivascular lymphocytic infiltrate in the upper dermis were observed. In a review of the literature we encountered only 5 reports of a similar clinicopathologic picture. The term “persistent supravenous erythematous eruption” (PSEE) seems suitable to describe this rare and peculiar cutaneous eruption that develops after intravenous cytotoxic drug treatment. (J Am Acad Dermatol 1998;39:839-42.)
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This article is made possible through an educational grant from Ortho Dermatological. |
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Reprint requests to: Ramon M. Pujol, MD, Department of Dermatology, Hospital de la Santa Creu I Sant Pau, Avda Sant Antoni M. Claret 167, 08025-Barcelona, Spain. E-mail: rmpujol@usa.net |
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0190-9622/98/$5.00 + 0 16/4/92742 |
Vol 39 - N° 5S
P. 839-842 - novembre 1998 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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