Multicentric reticulohistiocytosis associated with recurrent breast carcinoma - 09/09/11
Abstract |
Multicentric reticulohistiocytosis (MRH) is a rare systemic disorder that most often affects women in the fourth to fifth decades of life and is characterized by widespread cutaneous papules and nodules, often associated with a destructive arthritis. The characteristic histologic feature of the skin lesions, and of other affected organs, is the presence of histiocytes and multinucleated giant cells containing abundant eosinophilic cytoplasm with a “ground glass appearance.” Approximately 30% of the patients have an underlying malignancy suggesting MRH may be a paraneoplastic phenomenon. We describe a case of MRH associated with recurrent, metastatic breast carcinoma. (J Am Acad Dermatol 1998;39:864-6.)
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This article is made possible through an educational grant from Ortho Dermatological. |
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Reprint requests: Brian Berman, MD, PhD, Department of Dermatology and Cutaneous Surgery, 1600 NW 10th Ave, Rosenstiel Medical Science Building 2023A, Miami, FL 33136. |
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0190-9622/98/$5.00 + 0 16/4/94089 |
Vol 39 - N° 5S
P. 864-866 - novembre 1998 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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