Melanoma-in-transit presenting as panniculitis - 09/09/11
Abstract |
Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report an unusual case of a patient who developed right leg lesions that were initially thought to be infectious in origin. There was no resolution of these lesions with antibiotic therapy, and the patient subsequently underwent an incisional biopsy that showed atypical S-100 positive cells within dermal vessels. On further questioning, the patient revealed that 20 years earlier she had a pigmented lesion removed from her right posterior calf. Review of that material revealed malignant melanoma, approximately 3.2 mm in depth. Although the patient was subsequently treated with a right groin lymph node dissection and isolated limb perfusion chemotherapy, she has continued to develop locally recurrent disease. This case is unusual both in terms of clinical presentation and interval of disease progression. (J Am Acad Dermatol 1998;39:876-8.)
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This article is made possible through an educational grant from Ortho Dermatological. |
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Reprint requests: Dr Antoinette F. Hood, Division of Dermatopathology, Department of Pathology, 550 N University Blvd, Suite 3274, Indianapolis, IN 46202. |
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0190-9622/98/$5.00 + 0 16/4/94090 |
Vol 39 - N° 5S
P. 876-878 - novembre 1998 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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