Lichenoid changes in mycosis fungoides - 11/09/11
Abstract |
Background: |
The lichenoid tissue reaction (LTR) is present in a variety of dermatoses. Numerous histologic variants of mycosis fungoides (MF) have also been described.
Objective: |
Our purpose was to analyze a subset of patients with mycosis fungoides (MF) who had a prominent LTR at the time of presentation.
Methods: |
Clinical and pathologic features were evaluated in 12 patients with MF and an LTR.
Results: |
The primary complaint was intense pruritus (in 10 of 12 patients). An accelerated course was noted in one half of the patients including four with Sézary syndrome. Four patients died: two with Sézary syndrome and two with extensive patch/plaque ME Lymphocyte atypia, prominent basal cell layer epidennotropism, and the presence of plasma cells and eosinophils may help to distinguish lichenoid MF from lichen planus.
Conclusion: |
A subset of patients with MF present with lichenoid changes. The pathologic features may have a striking resemblance to lichen planus. Our findings suggest that lichenoid changes in MF tend to be associated with intense pruritus and may connote a poor prognosis.
Le texte complet de cet article est disponible en PDF.| * | Presented in part at the 33rd Annual Meeting of the American Society of Dermatopathology, Washington, D.C., Feb. 7-9, 1996. |
Vol 36 - N° 3
P. 417-422 - mars 1997 Retour au numéro
Article précédent
- A study of large congenital melanocytic nevi and associated malignant melanomas: Review of cases in the New York University registry and the world literature
- Maria DeDavid, Seth J. Orlow, Nathalie Provost, Ashfaq A. Marghoob, Babar K. Rao, Carol L. Huang, Qasim Wasti, Alfred W. Kopf, Robert S. Bart
- Cyclosporine as maintenance therapy in patients with severe psoriasis
- Jerome Shupack, Elizabeth Abel, Eugene Bauer, Marc Brown, Lynn Drake, Ruth Freinkel, Cynthia Guzzo, John Koo, Norman Levine, Nicholas Lowe, Charles McDonald, David Margolis, Matthew Stiller, Bruce Wintroub, Carol Bainbridge, Sandra Evans, Susan Hilss, William Mietlowski, Christine Winslow, Jay E. Birnbaum
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?