Evaluation of hylan b gel as a soft-tissue augmentation implant material - 11/09/11
Abstract |
Background: The ideal soft tissue augmentation material should be an inert, safe, volume-filling material that is easy to use and remains in place over time. Hylan b gel, a cross-linked hyaluronic acid, may have many of these characteristics.
Objective: We assessed the potential value of hylan b gel as a soft tissue augmentation material.
Methods: A 12-month guinea pig model was used to investigate the tissue effects of hylan b gel versus "collagen" controls.
Results: Hylan b gel was found to be biologically compatible and stable in dermal tissues. At 1 year, only hylan b gel implants were evident (12 of 16 test sites).
Conclusion: In this model hylan b gel performed favorably when compared with the most commonly used soft-tissue augmentation products. The material possesses many desirable implant material characteristics. (J Am Acad Dermatol 1997;36:544-9.)
Le texte complet de cet article est disponible en PDF.Plan
From the Dermatology Clinical Research, Veterans Medical Center, and the University of California Medical Center, San Diego. |
|
Supported by Biomatrix, Inc., Ridgefield, N.J. |
|
Reprint requests: Daniel Piacquadio, MD, Dermatology Clinical Research, 111B, UCSD/VA Medical Center, 3350 La Jolla Village Dr., San Diego, CA 92161. |
|
*No institutional affiliation. |
|
♢ | 16/1/79206 |
Vol 36 - N° 4
P. 544-549 - avril 1997 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?