UVB phototherapy is an effective treatment for pruritus in patients infected with HIV - 11/09/11
Abstract |
Background: Pruritus in patients positive for HIV may be debilitating.
Objective: Our purpose was to evaluate the efficacy of UVB therapy in the treatment of pruritus in patients positive for HIV.
Methods: Twenty-one male HIV-positive patients with intractable pruritus (14 with eosinophilic folliculitis and 7 with primary pruritus) were treated three times weekly with UVB phototherapy. Pruritus was quantified with use of a subjective score of 0 (none) to 10 (severe).
Results: Mean CD4 counts at the initiation of therapy were 91.0 ± 31.9 cells/μl. Pruritus scores before and after treatment were 8.6 ± 0.4 and 2.2 ± 0.5, respectively (p < 0.001). The mean number of treatments to achieve maximal improvement was 20.7 ± 2.3, with a cumulative UVB dose of 3399.1 ± 597.4 mJ/cm2. No significant difference was found between the group with eosinophilic folliculitis and the group with primary pruritus.
Conclusion: UVB phototherapy can produce significant relief of pruritus and improvement in the quality of life in patients positive for HIV. (J Am Acad dermatol 1997;37:414-7.)
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 | Previously published in part as abstracts (Photodermatol Photoimmunol Photomed 1994;10:179 and Photochem Photobiol 1996;63:56s-57s). |
| Reprint requests: Henry W. Lim, MD, Department of Dermatology, Henry Ford Medical Center, 2799 West Grand Blvd., Detroit, MI 48202-2689. |
 | 0190-9622/97/$5.00 + 16/1/82984 |
Vol 37 - N° 3
P. 414-417 - septembre 1997 Retour au numéro
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