Epidermal hamartoma presenting as longitudinal pachyleukonychia: A new nail genodermatosis - 11/09/11
Reprint requests: R. Baran, 42, Rue des Serbes, 06400 Cannes, France.Abstract |
Background: Epidermal hamartomas involving the nail apparatus are uncommon.
Objective: Our purpose was to define the clinical, genetic, and histologic features of a unique nail abnormality.
Methods: We examined eight members of three generations who presented with an unusual nail abnormality, longitudinal pachyleukonychia, as a sole characteristic that appeared between the ages of 9 and 30 years. One nail was examined histologically.
Results: Histologic examination showed pronounced hyperplasia of the nail bed with papillomatosis. Cell nests of a sebaceous type were included in the epithelial digitations. This dysplasia was not accompanied by abnormalities affecting skin, hair, teeth, or sweat glands.
Conclusion: This unique epidermal hamartoma appears to be inherited as an autosomal dominant condition.
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Vol 35 - N° 5P1
P. 675-677 - novembre 1996 Retour au numéro
Article précédent
- Segmental vitiligo: Clinical findings in 208 patients
- Seung Kyung Hann, Ho Jung Lee
- Redefining the Sjögren-Larsson syndrome: Atypical findings in three siblings and implications regarding diagnosis
- James F Nigro, William B Rizzo, Nancy B Esterly
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