Association between cutaneous melanoma incidence rates among white US residents and county-level estimates of solar ultraviolet exposure - 20/10/11
, Christopher J. Johnson, MPH b, Zaria Tatalovich, PhD c, Myles Cockburn, PhD d, Melody J. Eide, MD, MPH e, Kevin A. Henry, PhD f, Sue-Min Lai, PhD, MS, MBA g, Sai S. Cherala, MD, MPH h, Youjie Huang, MD, DrPH, MPH i, Umed A. Ajani, MBBS, MPH a
Reprint requests: Thomas B. Richards, MD, Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Hwy NE (K-55), Atlanta, GA 30341-3717.Abstract |
Background |
Recent US studies have raised questions as to whether geographic differences in cutaneous melanoma incidence rates are associated with differences in solar ultraviolet (UV) exposure.
Objectives |
We sought to assess the association of solar UV exposure with melanoma incidence rates among US non-Hispanic whites.
Methods |
We assessed the association between county-level estimates of average annual solar UV exposure for 1961 to 1990 and county-level melanoma incidence rates during 2004 to 2006. We used Poisson multilevel mixed models to calculate incidence density ratios by cancer stage at diagnosis while controlling for individuals’ age and sex and for county-level estimates of solar UV exposure, socioeconomic status, and physician density.
Results |
Age-adjusted rates of early- and late-stage melanoma were both significantly higher in high solar UV counties than in low solar UV counties. Rates of late-stage melanoma incidence were generally higher among men, but younger women had a higher rate of early-stage melanoma than their male counterparts. Adjusted rates of early-stage melanoma were significantly higher in high solar UV exposure counties among men aged 35 years or older and women aged 65 years or older.
Limitations |
The relationship between individual-level UV exposure and risk for melanoma was not evaluated.
Conclusions |
County-level solar UV exposure was associated with the incidence of early-stage melanoma among older US adults but not among younger US adults. Additional studies are needed to determine whether exposure to artificial sources of UV exposure or other factors might be mitigating the relationship between solar UV exposure and risk for melanoma.
Le texte complet de cet article est disponible en PDF.Key words : dermatology/manpower, incidence, melanoma/epidemiology, population surveillance, registries, skin neoplasms/epidemiology, socioeconomic factors, solar ultraviolet rays/adverse effects
Abbreviations used : AVGLO, NPCR, RUCC, SEER, SES, UV
Plan
| Publication of this supplement to the JAAD was supported by the Division of Cancer Prevention and Control, Centers for Disease Control and Prevention (CDC). Dr Eide was supported by a Dermatology Foundation Cancer Development Award in Health Care Policy. |
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| Conflicts of interest: None declared. |
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| The opinions or views expressed in this supplement are those of the authors and do not necessarily reflect the opinions, recommendations, or official position of the journal editors or the Centers for Disease Control and Prevention. |
Vol 65 - N° 5S1
P. S50.e1-S50.e9 - novembre 2011 Retour au numéro
Article précédent
- Melanoma in adolescents and young adults (ages 15-39 years): United States, 1999-2006
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- Association of cutaneous melanoma incidence with area-based socioeconomic indicators–United States, 2004-2006
- Simple D. Singh, Umed A. Ajani, Christopher J. Johnson, Katherine B. Roland, Melody Eide, Ahmedin Jemal, Serban Negoita, Rana A. Bayakly, Donatus U. Ekwueme
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