Lymphome intestinal associé à une maladie de Behçet - 16/02/08
Mohammed Habib HOUMAN [1],
Imed BEN GHORBEL [1],
Saloua B'CHIR-HAMZAOUI [1],
Mounir LAMLOUM [1],
Nidhameddine KCHIR [2],
Mohamed MILED [1]
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Intestinal Behçet's disease associated with intestinal non-hodgkin's lymphoma |
The association of Behçet's disease and non-Hodgkin's lymphoma is very rare. The first case of primary intestinal lymphoma with intestinal Behçet's disease is reported.
A 37 year-old woman had been treated for Behçet's disease with colchicine for 2 years. In July 1997, she developed uveitis and was treated by monthly intravenous pulses of cyclophosphamide for 6 months, but uveitis persisted ; so cyclophosphamide was replaced by cyclosporin 300 mg/day. One month later, she suffered from diarrhea. Colonoscopy showed ileocoecal ulcerations. Histological examination of surgical biopsy revealed B large cell type lympocytic malignant lymphoma and vasculitis lesions compatible with intestinal Behçet's disease. Cyclosporin was stopped and treatment with prednisone was instituted.
The relationship between non-Hodgkin's lymphoma and immunosuppressive drugs in Behçet's disease is discussed.
Mots clés : Maladie de Behçet , Vascularite , Lymphome malin non-hodgkinien
Keywords:
Behçet's disease
,
Vasculitis
,
Non-Hodgkin's lymphoma
© 2001 Elsevier Masson SAS. Tous droits réservés.
Vol 152 - N° 6
P. 415-418 - octobre 2001 Retour au numéro
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