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Incidence of psoriasis in children: A population-based study - 24/04/13

Doi : 10.1016/j.jaad.2009.07.029 
Megha M. Tollefson, MD a, Cynthia S. Crowson, MS b, Marian T. McEvoy, MD a, Hilal Maradit Kremers, MD, MSc b,
a Department of Dermatology, College of Medicine, Mayo Clinic, Rochester, Minnesota 
b Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota 

Reprint requests: Hilal Maradit Kremers, MD, MSc, Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

Abstract

Background

Although psoriasis is considered to have a dual peak in age of onset, currently no studies exist regarding the incidence of psoriasis in children.

Objective

The objective of this study was to determine the incidence of psoriasis in childhood.

Methods

A population-based incidence cohort of patients aged younger than 18 years first given the diagnosis of psoriasis between January 1, 1970, and December 31, 1999, was assembled. The complete medical record of each child was reviewed and psoriasis diagnosis was validated by a confirmatory diagnosis in the medical record by a dermatologist or medical record review by a dermatologist. Age- and sex-specific incidence rates were calculated and were age and sex adjusted to 2000 US white population.

Results

The overall age- and sex-adjusted annual incidence of pediatric psoriasis was 40.8 per 100,000 (95% confidence interval: 36.6-45.1). When psoriasis diagnosis was restricted to dermatologist-confirmed subjects in the medical record, the incidence was 33.2 per 100,000 (95% confidence interval: 29.3-37.0). Incidence of psoriasis in children increased significantly over time from 29.6 per 100,000 in 1970 through 1974 to 62.7 per 100,000 in 1995 through 1999 (P < .001). Chronic plaque psoriasis was the most common type (73.7%), and the most commonly involved sites were the extremities (59.9%) and the scalp (46.8%).

Limitations

The population studied was a mostly white population in the upper Midwest.

Conclusion

The incidence of pediatric psoriasis increases with increasing age. There is no apparent dual peak in incidence. The incidence of pediatric psoriasis increased in recent years in both boys and girls.

Le texte complet de cet article est disponible en PDF.

Key words : epidemiology, population-based study, psoriasis


Plan


 Funded by an unrestricted research grant from Amgen Inc and National Institute of Arthritis and Musculoskeletal and Skin Diseases AR30582.
 Conflicts of interest: None declared.


© 2009  American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
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Vol 62 - N° 6

P. 979-987 - juin 2010 Retour au numéro
Article précédent Article précédent
  • The safety profile and sustained remission associated with response to multiple courses of intramuscular alefacept for treatment of chronic plaque psoriasis
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  • The Journal of the American Academy of Dermatology and The Journal of Allergy and Clinical Immunology Announce a Shared Science Program

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