Skin cancers, blindness, and anterior tongue mass in African brothers - 24/04/13

Doi : 10.1016/j.jaad.2008.06.030

Priya Mahindra, BA ^a,^b, John J. DiGiovanna, MD ^a,^c, Deborah Tamura, RN, MS ^a, Jaime S. Brahim, DDS, MS ^d, Thomas J. Hornyak, MD, PhD ^e, Jere B. Stern, MD ^f, Chyi-Chia Richard Lee, MD, PhD ^f, Sikandar G. Khan, PhD ^a, Brian P. Brooks, MD, PhD ^g, Janine A. Smith, MD ^g, Brian P. Driscoll, MD ^h, Andrew D. Montemarano, DO ⁱ, Kate Sugarman, MD ^j, Kenneth H. Kraemer, MD ^a,^⁎
^a Basic Research Laboratory, DNA Repair Section, Center for Cancer Research, National Cancer Institute, Bethesda, MD
^b Clinical Research Training Program, National Institutes of Health, Bethesda, MD
^c Division of Dermatopharmacology, Department of Dermatology, The Warren Alpert School of Medicine of Brown University, Providence, RI
^d National Institute of Dental and Craniofacial Research, Bethesda, MD
^e Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD
^f Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD
^g National Eye Institute, Bethesda, MD
^h National Institute of Deafness and other Communication Disorders, Bethesda, MD
ⁱ Skin Cancer Surgery Center, Bethesda, MD
^j Community of Hope Health Services, Washington, DC

Reprint requests: Dr Kenneth H. Kraemer, National Cancer Institute, Basic Research Laboratory, Bldg 37, Room 4002, MSC 4258, Bethesda, MD 20892-4258.

Abbreviations used : BCC, NER, SCC, UV, XP

Plan

Case summary

History

Physical examination

Diagnostic studies and treatment

Supported by the Intramural Research Programs of the Center for Cancer Research, National Cancer Institute, of the National Institute of Dental and Craniofacial Research, of the National Eye Institute, and of the National Institute of Deafness and other Communication Disorders of the National Institutes of Health (NIH). Support for author Mahindra was made possible through the Clinical Research Training Program, a public-private partnership supported jointly by the NIH and Pfizer Inc (via a grant to the Foundation for NIH from Pfizer Inc).

Conflicts of interest: None declared.