Kikuchi’s disease: Case report and systematic review of cutaneous and histopathologic presentations - 24/04/13
Abstract |
Kikuchi’s disease, also known as histiocytic necrotizing lymphadenitis, is a systemic illness with classic clinical findings of cervical lymphadenopathy and fever. Diagnosis is confirmed by lymph node histology, which reveals paracortical foci of necrosis and a histiocytic infiltrate. Kikuchi’s disease has been associated with a number of infections, but no single source has been identified. Diverse, often nonspecific, cutaneous findings have been described in up to 40% of cases. Description of the histopathologic findings of skin lesions is limited to single case reports and one case series. We describe a 24-year-old woman with fevers, lymphadenopathy, hepatic and hematologic abnormalities, and a skin eruption involving the face, neck, trunk, and extremities with characteristic lymph node and cutaneous histopathologic findings. We completed a systematic review of the clinical presentations and histopathology of Kikuchi’s disease.
Le texte complet de cet article est disponible en PDF.Abbreviations used : ANA, SLE
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
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Presented in poster format at the annual meeting of the American Academy of Dermatology, Washington, DC, February 2-6, 2007. |
Vol 59 - N° 1
P. 130-136 - juillet 2008 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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