A 57-year-old Caucasian man presented with multiple asymptomatic spiny papules on the palms and soles that he had been shaving off with a razor for many years. He was otherwise healthy with no personal or family history of skin disease or malignancy. A diagnosis of spiny keratoderma of the palms and soles or “music box spine dermatosis” was made. The clinical, histologic, and electron-microscopic features of spiny keratoderma are distinct. This entity previously had multiple classifications and it is important to distinguish it from other keratodermas as some keratodermas can be linked to cutaneous and internal malignancies and conditions: polycystic kidney disease, liver cysts, Darier’s disease, and hyperlipoproteinemia among others. Spiny keratodermas can have systemic associations and do not resolve spontaneously. Treatment is generally ineffective.Le texte complet de cet article est disponible en PDF.
| Supported by National Institutes of Health National Institute of Arthritis, Musculoskeletal and Skin Diseases RO1 AR 049284, and the National Institutes of Health Case Skin Diseases Research Center P30-AR 39750 (Dr Gilliam).
| Conflicts of interest: None declared.
| Presented in the oral session “Duels for Dermatopathology” at the American Society of Dermatopathology, Seattle, Washington, October 20, 2005.
| Reprints not available from the authors.