Zinc is a trace element essential to the gastrointestinal, immune, integumentary, reproductive, and central nervous systems. Zinc deficiency is prevalent in many areas of the world and is a diagnostically challenging condition. Cutaneous manifestations typically occur in moderate to severe zinc deficiency and present as alopecia and dermatitis in the perioral, acral, and perineal regions. Zinc deficiency is a potentially fatal disease process. The aim of this review is to focus on the cutaneous manifestations, diagnosis, and treatment of zinc deficiency in children, and to propose an etiologic classification system.Le texte complet de cet article est disponible en PDF.
Key words : acrodermatitis enteropathica, micronutrients, pediatric, zinc absorption, zinc deficiency, zinc metabolism
Abbreviations used : AE, IL, MMP, NF, ROS, SLC
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