The acute and chronic consequences of ultraviolet radiation on human skin are reviewed. An awareness of variations in naturally occurring photoprotective agents and the use of glass, sunglasses, and fabric can lead to effective protection from the deleterious effects of ultraviolet radiation. New systemic agents, including Polypodium leucotomos, afamelanotide, and antioxidants have potential as photoprotective agents.Le texte complet de cet article est disponible en PDF.
Key words : afamelanotide, antioxidants, glass, photoprotection, photoprotective agents, physical systemic photoprotective agents, ultraviolet radiation
Abbreviations used : α-MSH, AO, BCC, IPD, IR, MMP, NMSC, NSAID, PPD, ROS, SCC, SPF, UVA, UVB, UVC, UPF, UVR, UCA, VL
| Funding sources: None.
| Dr Lim has served as consultant for Ferndale, La Roche-Posay, Pierre Fabre, Uriage, and Palatin. He has received research grants from Clinuvel and Estee Lauder. Mr Osterwalder is a full time employee of BASF. Dr Wang has served on the advisory board of L'Oreal. Drs Burnett and Jansen have no conflicts of interest to declare.